abstract：:We have developed an inexpensive, microcomputer-based, multiuser hard disk system for surgical pathology that uses a commercially available word processor and data base manager, linked together by several BASIC programs written by us. System functions include keyboard input of patient demographic data and specimen inf...

journal_title：Archives of pathology & laboratory medicine

authors： Talamo TS,Losos FJ 3rd

更新日期：1985-01-01 00:00:00

abstract：:A 9-year-old boy with metachromatic leukodystrophy (MLD) was found to have diffuse papillomatosis of the gallbladder that was virtually obliterating the lumen of the gallbladder. To our knowledge, two other examples of this lesion have been reported previously in MLD. ...

journal_title：Archives of pathology & laboratory medicine

authors： Burgess JH,Kalfayan B,Slungaard RK,Gilbert E

更新日期：1985-01-01 00:00:00

abstract：:The College of American Pathologists' enzyme survey permits the evaluation of the quality of enzyme analyses in clinical laboratories. Animal source enzymes for lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase, and creatine kinase are satisfactory as supplements for enzyme survey serum, sinc...

journal_title：Archives of pathology & laboratory medicine

authors： Lott JA,Tholen DW,Massion CG

更新日期：1984-12-01 00:00:00

abstract：:Granular cell tumors occur in a variety of sites, including the breast (6%). Origins from histiocytic, myogenic, fibroblastic, and neurogenic elements have been proposed. Female predominance suggests that estrogenic hormones are involved. Four granular cell tumors of the breast and one in an axillary lymph node were s...

journal_title：Archives of pathology & laboratory medicine

authors： Ingram DL,Mossler JA,Snowhite J,Leight GS,McCarty KS Jr

更新日期：1984-11-01 00:00:00

abstract：:We studied 16 cases of bile duct adenomas, lesions that are distinct from Meyenburg complex. The former lesion is made up of small tubular structures with little or no lumen, is usually single and subcapsular, and is unrelated to cystic disease. It must be differentiated from early carcinoma. Of the six cases encounte...

journal_title：Archives of pathology & laboratory medicine

authors： Govindarajan S,Peters RL

更新日期：1984-11-01 00:00:00

abstract：:In hyperlipemic swine, areas of the aortic arch that accumulate intravenously injected Evans blue dye (blue areas) appear to be more susceptible to early atherogenesis than adjacent areas that are devoid of dye uptake (white areas). We used immunofluorescence microscopy to determine the localization of apoprotein-B (a...

journal_title：Archives of pathology & laboratory medicine

authors： Feldman DL,Hoff HF,Gerrity RG

更新日期：1984-10-01 00:00:00

abstract：:We reviewed the clinicopathologic features of 17 androgenic granulosa cell tumors. The patients, two of whom were pregnant, ranged from 2 to 58 years of age (average age, 22.5 years). Fourteen of the patients were masculinized as evidenced by various combinations of facial acne, temporal recession of hair, clitorimega...

journal_title：Archives of pathology & laboratory medicine

authors： Nakashima N,Young RH,Scully RE

更新日期：1984-10-01 00:00:00

abstract：:A review was made of the clinical histories, treatment, and renal histologic features of 12 patients with anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM disease). Two patients had milder histopathologic changes in their kidney biopsy specimens and achieved clinical remission. The other...

journal_title：Archives of pathology & laboratory medicine

authors： Stave GM,Croker BP

更新日期：1984-09-01 00:00:00

abstract：:True uterine diverticulum is an exceedingly rare entity. We report only the second case, to our knowledge, of a nulliparous uterus containing a diverticulum communicating with the endometrial cavity. True uterine diverticula probably arise from a localized duplication of the distal Müllerian duct on one side. They may...

journal_title：Archives of pathology & laboratory medicine

authors： Engel G,Rushovich AM

更新日期：1984-09-01 00:00:00

abstract：:We examined psammoma bodies at the ultrastructural level within meningocytic whorls in nine cases of meningioma. The cells comprising the meningocytic whorls displayed the typical fine structural characteristics of meningothelial cells. The extracellular spaces contained amorphous substances in some whorls and interst...

journal_title：Archives of pathology & laboratory medicine

authors： Kubota T,Hirano A,Sato K,Yamamoto S

更新日期：1984-09-01 00:00:00

abstract：:Perfluorochemicals have been shown to have a high affinity for oxygen and therefore, have potential use in circumstances in which conventional blood transfusions are not possible. We examined by light and electron microscopy (EM) histologic changes in liver, spleen, lung, and kidney of rabbits each infused with 20 to ...

journal_title：Archives of pathology & laboratory medicine

authors： Nanney L,Fink LM,Virmani R

更新日期：1984-08-01 00:00:00

abstract：:A patient with sarcoidosis had a biopsy of a firm nontender breast nodule that at analysis disclosed multiple noncaseating granulomas. In another patient with sarcoidosis, noncaseating granulomas were an incidental finding in a mastectomy specimen containing medullary carcinoma and in two subsequent biopsy specimens o...

journal_title：Archives of pathology & laboratory medicine

authors： Gansler TS,Wheeler JE

更新日期：1984-08-01 00:00:00

abstract：:Striated muscle cells coexisting with neuroglial tissue were found in the leptomeninges of a 3-day-old neonate. An immunohistochemical study demonstrated the presence of myoglobin in the striated muscle cells, glial fibrillary acidic protein, and S-100 protein in the heterotopic glia, S-100 protein in the Schwann cell...

journal_title：Archives of pathology & laboratory medicine

authors： Nakamura Y,Nakashima T,Komatsu Y,Hashimoto T,Hachisuka H

更新日期：1984-07-01 00:00:00

abstract：:Tubuloreticular inclusions have been described with sufficient frequency in certain tissues of patients with systemic lupus erythematosus (SLE) to make the finding of such inclusions helpful in making a diagnosis of this disorder. The finding of such inclusions in lung biopsy specimens, however, has been distinctly ra...

journal_title：Archives of pathology & laboratory medicine

authors： Lyon MG,Bewtra C,Kenik JG,Hurley JA

更新日期：1984-07-01 00:00:00

abstract：:Questionnaires sent to representative medicolegal jurisdictions in the United States showed that medicolegal necropsies comprise a substantial proportion of the total number of autopsies performed. Qualitative differences between customary hospital autopsies and their forensic counterparts include autopsy bias, the im...

journal_title：Archives of pathology & laboratory medicine

authors： Hirsch CS

更新日期：1984-06-01 00:00:00

abstract：:In 4% formaldehyde-fixed, paraffin-embedded tissues, PAS negativity for mycobacteria in the literature has been axiomatic. However, recent observations of disseminated human mycobacteriosis have shown that intracellular (phagocytosed) organisms stained strongly positive with the routine PAS technique. This staining wa...

journal_title：Archives of pathology & laboratory medicine

authors： Pappolla MA,Mehta VT

更新日期：1984-05-01 00:00:00

abstract：:The potential for the establishment of predictive assays for cancer chemotherapy was generated recently by the development of a soft agar clonogenic assay for human tumor cells. Though the assay technique is promising, certain technical problems remain. One is the difficulty of preparing viable cell suspensions from s...

journal_title：Archives of pathology & laboratory medicine

authors： Katoh AK,Charoensiri S,Fogarty P,Best C

更新日期：1984-04-01 00:00:00

abstract：:Synovitic symptoms and radiologically documented cystic lesions in several carpal bones and distal radius developed two years after the implantation of silicone rubber scaphoid prosthesis for pseudoarthrosis. Open biopsy revealed granulomatous synovitis and osteitis and foreign material in carpal tissues. Ultrastructu...

journal_title：Archives of pathology & laboratory medicine

authors： Ekfors TO,Aro H,Mäki J,Aho AJ

更新日期：1984-03-01 00:00:00

abstract：:We performed x-ray microanalysis of autopsy specimens using a scanning-transmission electron microscopy mode. Tissues were obtained at necropsy from a patient with history of angiography using thorium dioxide and from a patient with hemochromatosis. X-ray microanalysis confirmed the presence of thorium and iron in the...

journal_title：Archives of pathology & laboratory medicine

authors： Landas S,Turner JW,Moore KC,Mitros FA

更新日期：1984-03-01 00:00:00

abstract：:Hepatic tumors unassociated with cirrhosis were encountered in seven patients aged 10 to 19 years. Four patients had received androgens for aplastic anemia. Two patients had transfusional hemosiderosis. One patient had had a renal transplant 2 1/2 years ago. Two patients are alive at 2 3/4 and 2 1/2 years after surgic...

journal_title：Archives of pathology & laboratory medicine

authors： Chandra RS,Kapur SP,Kelleher J Jr,Luban N,Patterson K

更新日期：1984-02-01 00:00:00

abstract：:Monoclonal antibodies elicited to surface antigens on a wide variety of normal and neoplastic cell types have been used with increasing frequency in the diagnosis and classification of cancer. Their widest application so far has been in the in vitro analysis of leukemia and lymphoma using blood or bone marrow samples ...

journal_title：Archives of pathology & laboratory medicine

authors： Borowitz MJ,Stein RB

更新日期：1984-02-01 00:00:00

abstract：:When present, chromosome abnormalities can contribute useful information for tumor diagnosis and prognosis. However, the existence of diploid tumor cells indicates that such abnormalities are not necessary in tumors. Their time of appearance, sometimes preceding or predisposing to tumor and sometimes occurring late in...

journal_title：Archives of pathology & laboratory medicine

authors： Wolman SR

更新日期：1984-01-01 00:00:00

abstract：:The utility of a laboratory test for differential diagnosis depends on the degree that test results for different disease states overlap. I developed a new overlap index that ranges from zero, for an ideal test with no overlap, to one if the median test result is the same for the two disease states. The index does not...

journal_title：Archives of pathology & laboratory medicine

authors： Hartz AJ

更新日期：1984-01-01 00:00:00

abstract：:Localized aggregates of amyloid and chronic inflammatory cells are well known to occur in conjunctiva and usually are not associated with systemic disease. This study reports one such case in a healthy young man. In this lesion, the plasma cell infiltrate was shown by immunofluorescence to contain IgD lambda. The amyl...

journal_title：Archives of pathology & laboratory medicine

authors： Schaldenbrand JD,Keren DF

更新日期：1983-12-01 00:00:00

abstract：:The morphologic and biochemical characterization of cytocontractile and cytoskeletal elements in a given cell or tissue appears more and more as a useful tool in the study of differentiation phenomena, the origin of various human tumors (including metastases), and the degree of cellular adaptation during physiologic a...

journal_title：Archives of pathology & laboratory medicine

authors： Gabbiani G,Kocher O

更新日期：1983-12-01 00:00:00

abstract：:Recombinant DNA technology has already had a major impact on our understanding of microbiology, cell biology, and genetic diseases and it will certainly have extensive applications in laboratory medicine. The techniques of restriction endonuclease analysis of DNA, nucleic acid hybridization after electrophoretic separ...

journal_title：Archives of pathology & laboratory medicine

authors： Rabson AB,Rabson AS

更新日期：1983-10-01 00:00:00

abstract：:Quantitation of T and B lymphocytes in infants and children is an important test in the diagnosis of a suspected immuno-deficiency. Previous studies indicated that the absolute and relative numbers of lymphocyte subpopulations vary with age, but these data in the pediatric age group are incomplete and often contradict...

journal_title：Archives of pathology & laboratory medicine

authors： Hicks MJ,Jones JF,Minnich LL,Weigle KA,Thies AC,Layton JM

更新日期：1983-10-01 00:00:00

abstract：:A 57-year-old woman with rheumatoid arthritis and alpha 1-antitrypsin deficiency (PiMZ phenotype), recovering from intraabdominal sepsis in association with gastric ulcer perforation, had portal hypertension. An operative liver biopsy specimen showed a distinctive elastosis of the portal tracts without cirrhosis. ...

journal_title：Archives of pathology & laboratory medicine

authors： Lee FI,Kelly JK,Vasudev KS

更新日期：1983-09-01 00:00:00

abstract：:Presented herein are the rationale, evolution, and present status of the alcian blue (AB)-aldehyde pararosaniline (AP) method for the selective staining of pancreatic beta-cell granules in paraffin sections of fixed tissues. Acidic mucins of pancreatic ductal and ductular cells and granules of mast cells and basophils...

journal_title：Archives of pathology & laboratory medicine

authors： Mowry RW

更新日期：1983-09-01 00:00:00

abstract：:The role of the Ito cells in perivenular and intralobular scarring in alcoholic liver disease was examined morphologically. There was a substantial decrease in the number of Ito cells in the midzone of the hepatic lobule in both fatty liver and alcoholic hepatitis as judged by light microscopy. By electron microscopy,...

journal_title：Archives of pathology & laboratory medicine

authors： Okanoue T,Burbige EJ,French SW

更新日期：1983-09-01 00:00:00

abstract：:Primary leiomyosarcoma of bone is extremely rare. A 60-year-old woman had a mass in the right femur that was studied immunohistochemically and by electron microscopy. Human smooth-muscle actomyosin was detected in tumor cells, but human skeletal-muscle myoglobin and lysozyme (muramidase) were not. Electron microscopy ...

journal_title：Archives of pathology & laboratory medicine

authors： Kawai T,Suzuki M,Mukai M,Hiroshima K,Shinmei M

更新日期：1983-08-01 00:00:00

abstract：:Atherosclerosis can be defined as a disease process that occurs when the influx and deposition of cholesterol into the arterial wall exceed the egress of cholesterol from the arterial wall. This process is characterized by early deposition of cholesterol in and around arterial wall cells. The cholesterol is derived fr...

journal_title：Archives of pathology & laboratory medicine

authors： Mahley RW

更新日期：1983-08-01 00:00:00

abstract：:Toxoplasmosis of both donor and recipient hearts was diagnosed by means of endomyocardial biopsy specimens after heterotopic cardiac transplantation for dilated cardiomyopathy. Before transplantation, the donor had raised antibody titers to Toxoplasma, and the recipient was negative. When toxoplasmosis was diagnosed o...

journal_title：Archives of pathology & laboratory medicine

authors： Rose AG,Uys CJ,Novitsky D,Cooper DK,Barnard CN

更新日期：1983-07-01 00:00:00

abstract：:Using the formaldehyde-induced fluorescence method, we found a peculiar rosary-type swelling of the adrenergic axons in the peripheral nerves, deficiency of the perivascular adrenergic plexuses in the visceral and cerebral arteries, and reduction of noradrenergic fluorescence in the tegmental and hypothalamic regions ...

journal_title：Archives of pathology & laboratory medicine

authors： Uno H,Arya S,Laxova R,Gilbert EF

更新日期：1983-06-01 00:00:00

abstract：:We studied a woman who underwent a jejunoileal bypass for the treatment of morbid obesity and in whom severe jaundice and hepatic failure developed six months later; these developments prompted restoration of the normal continuity of the small bowel. Four serial wedge biopsy specimens of the liver were taken during a ...

journal_title：Archives of pathology & laboratory medicine

authors： Allam C,Bala'a M,Shamma'a M

更新日期：1983-04-01 00:00:00

abstract：:To study the natural course of catheter-induced endocarditis secondarily infected with Staphylococcus epidermidis, 29 rabbits had catheters introduced surgically through the carotid artery to the aortic valve. Forty-eight hours later the catheters were removed from five rabbits. The rabbits were inoculated intravenous...

journal_title：Archives of pathology & laboratory medicine

authors： Shamsuddin D,Tuazon CU,Miller H,Shamsuddin AK,Friedman D

更新日期：1983-03-01 00:00:00

abstract：:A retrospective study was performed to describe the histologic stages of selective myocardial cell necrosis (SMCN) in nonhuman primates, and to compare the incidence of SMCN in two groups of nonhuman primates. Myocardial tissues taken at the time of autopsy from 50 primates at an experimental center were compared with...

journal_title：Archives of pathology & laboratory medicine

authors： Cowan MJ,Giddens WE Jr,Reichenbach DD

更新日期：1983-01-01 00:00:00

abstract：:We studied the use of stat (ie, statim--as soon as possible) laboratory tests at a university teaching hospital. For the 20 most frequently performed tests, 35.7% of the determinations were performed on a stat basis. The frequency with which a test was ordered on a stat basis ranged from 6.0% (for ESR) to 61.5% (amyla...

journal_title：Archives of pathology & laboratory medicine

authors： Chu RC,Williams SV,Eisenberg JM

更新日期：1982-12-01 00:00:00

abstract：:A pathogenetic relationship between hepatic manifestations of alpha 1-antitrypsin deficiency (AATD) and hepatocellular carcinoma has previously been suggested but not established. We encountered three patients with hepatocellular carcinoma (HCC) and nonneoplastic hepatocytes containing globules positive for alpha 1-an...

journal_title：Archives of pathology & laboratory medicine

authors： Rubel LR,Ishak KG,Benjamin SB,Knuff TE

更新日期：1982-12-01 00:00:00

abstract：:A case of epithelioid sarcoma was studied light microscopically, ultrastructurally, and immunohistologically. The tumor was a deep antebrachial mass in a 57-year-old man, and led to antebrachial amputation. Light microscopically, the tumor consisted of nodules that often had central necrosis. The cells were uniform, w...

journal_title：Archives of pathology & laboratory medicine

authors： Miettinen M,Lehto VP,Vartio T,Virtanen I

更新日期：1982-11-01 00:00:00